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DSC Measurements on DMPC with Pentanol and Hexanole
Internt-fagligt, 2. modul, 2008, id:251
Vejleder:Dorthe Posselt
Findes på RUb:Ja
English abstract
In (Heimburg and Jackson, 2007) Thomas Heimburg and Andrew D. Jackson propose a model /HJ-model) for the heat capacity curves of lipids containing anaesthesia. The model is suggested as an explanation of the so-called Meyer-Overton rule. The aim of this report is to study how well this model corresponds to heat capacity curves, for 1,2-Dimyristoyl-sn-Glycero-3-Phosphocholine (DMPC) membranes containing pentanol or hexanol, measured on the Perkin Elmer Diamond Differential Scanning Calorimeter (DSC) at IMFUFA, Roskilde University Center. Due to several calibration failures and instrumental errors we were unable to produce heat capacity curves that could constitute a decent basis for an evaluation for the model. We would like to stress that this inconclusiveness was in no way due to the model itself.

Database opslag den: 21-09-2017